Aspirin Capsule Animation
Science & Technology
Introduction
Basilor has developed an innovative formulation designed to ensure the targeted release of aspirin in specific portions of the gastrointestinal tract. Upon entering the stomach, the capsule dissolves and releases its liquid aspirin lipid matrix. This matrix has been meticulously formulated to prevent the release of aspirin in the low pH environment of the stomach.
Once the lipid matrix passes into the duodenum, naturally secreted digestive agents, such as bicarbonate and bile, emulsify it. This process transforms the lipid suspension into large vesicles, which are subsequently broken down into smaller aspirin-containing micelles that can be efficiently absorbed by the body.
In the event of reflux, the low stomach pH causes the large vesicles to reaggregate, forming a stable complex that prevents aspirin from coming into direct contact with the stomach lining. When reintroduced to the duodenum, the aspirin is re-released and continues its journey for absorption, ultimately delivering its life-saving benefits to the patient.
Keywords
- Basilor
- Innovative formulation
- Targeted release
- Gastrointestinal tract
- Liquid aspirin
- Lipid matrix
- Bicarbonate
- Bile
- Emulsification
- Micelles
- Absorption
- Reflux
- Stable complex
FAQ
Q: What is the purpose of Basilor's innovative formulation?
A: The purpose is to ensure the targeted release of aspirin in specific portions of the gastrointestinal tract.
Q: How does the capsule behave when it reaches the stomach?
A: In the stomach, the capsule dissolves and releases its liquid aspirin lipid matrix, which prevents aspirin release in the low pH environment.
Q: What happens to the lipid matrix after it leaves the stomach?
A: The lipid matrix is emulsified in the duodenum by digestive agents like bicarbonate and bile, forming micelles for absorption.
Q: What occurs during reflux and how does it protect the stomach?
A: During reflux, the low stomach pH causes large vesicles to come together, holding the aspirin in a stable complex to prevent direct contact with the stomach lining.
Q: How does aspirin continue to be effective after re-releasing in the duodenum?
A: After re-releasing in the duodenum, aspirin can continue to be absorbed, delivering its life-saving benefits.
